Anabolicum (LGD-4033)

Intro

Anabolicum, also known as LGD-4033, is a Selective Androgen Receptor Modulator (SARM). Like all SARM’s, they were developed to treat muscle wasting diseases. Athletes have discovered it as a performance enhancing compound, to help them achieve their goals as I will discuss in this article.

Development

Anabolicum is currently in clinical testing after being discovered by Ligand Pharma (1)Ligand Presents New Preclinical Data on its Lead SARM Molecule LGD-4033 at the Gerontological Society of America Annual Meeting in 2009. Exchange Act File No. 001-33093 , and is still being developed by Viking Therapeutics. In pre-clinical trials, monkeys showed ‘significant’ body mass gain after 13 weeks with no adverse effects. In clinical trials on humans, there was an increase in lean body mass after 3 weeks with no negative side effects observed (2)The Safety, Pharmacokinetics, and Effects of LGD-4033, a Novel Nonsteroidal Oral, Selective Androgen Receptor Modulator, in Healthy Young Men, J Gerontol A Biol Sci Med Sci, PMC4111291. It is currently in Phase 2 clinical trials, which started in late 2016, to see the results of the compound being given to people who were suffering from hip fractures and ailments.

Science of how it works

buy lgd-4033Anabolicum (LGD-4033) works by binding to the androgen receptors selectively, specifically the bone and muscle. This end result means an enhanced muscle building (anabolic activity), and it will prevent muscle wasting (catabolism). Athletes have reported gains in pure lean muscle mass of several pounds after 8 weeks on, with solid gains in their weight lifts. Those who are in endurance sports like Crossfit have decreased their times on their exercises and boot camps.

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Other things it does

Anabolicum works similar to ostabolic and frankly is underrated when it comes to its bone and soft tissue improvement properties. It will strengthen bones and muscles around the joints, making it an excellent healing SARM. It manages to do this without exhibiting negative side effects like anabolic steroids will.

Scenarios of use and How to stack

Anabolicum can be run alone for an increase in lean muscle, strength, and joint strengthening. But it is popularly used as part of several stacks.

Healing Stack

buy mk-2866The first stack is great if you are trying to recover from injury and that is stacking it with Ostabolic. You can also add N2jointrx to the stack and your recovering time from any injury will be reduced significantly. When I tore my tricep and rotator cuff, I could not sleep the first few days from the pain, and I can tell you within 2 weeks of using this stack the pain was reduced substantially and a week later I was back in the gym lifting again.

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Bridging Stack

The next is called a bridging stack. You would run the Anabolicum along with Andarine in between cycles to increase lean muscle and strength and avoiding catabolism. This gives you the advantage of going into your next cycle stronger and more muscular than you would have been otherwise.

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Other Uses

Finally, many steroid users will add in Anabolicum because it will provide more anabolic properties to your cycle without adding to side effects. I like to add it to all my steroid cycles because it helps with nagging injuries and helps with vascularity and lean muscle gains.

Quiz: What Other SARMS Should You Stack With LGD-4033?

The King Of Bulking

LGD4033 + S4

The King Of Recomposition

Side effects

Anabolicum side effects are very low since it exhibits an 80/0 anabolic to androgenic ratio. However you can expect some suppression from this compound, so it is important when using it to always run a mini-PCT.
Anabolicum does not display any estrogenic, androgenic, or liver strain side effects. In females, it will not cause virilization symptoms.

half life and detection times

Anabolicum has approximately a 30 hour half life, which is excellent, and means you can easily get away with dosing it once daily only. The detection time is about 2-4 weeks, so a tested athlete should stop taking it at least a month before their test is due.

Dosage and how to take

LGD-4033 is ran an average of 10mg a day with males, and 5mg a day for females. If you are using it in research chemical liquid form I recommend squirting it in the mouth and swallowing, then chasing it down with juice. Do not mix it in your drink first, and do not let it absorb under your tongue as the taste is awful.

Where to find

Anabolicum can be found legally in pill or capsulated form, however, keep in mind if you purchase it like that it is going to be underdosed or laced with pro hormones. Raw Anabolicum in its purest form can only legally be sold as a liquid research chemical, and I have found the only company that has 99.9% pure compound is at sarms1.com.

References   [ + ]

1. Ligand Presents New Preclinical Data on its Lead SARM Molecule LGD-4033 at the Gerontological Society of America Annual Meeting in 2009. Exchange Act File No. 001-33093
2. The Safety, Pharmacokinetics, and Effects of LGD-4033, a Novel Nonsteroidal Oral, Selective Androgen Receptor Modulator, in Healthy Young Men, J Gerontol A Biol Sci Med Sci, PMC4111291

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