Cardarine (GW-501516)

Intro

Cardarine/GW-501516 is a PPAR (Peroxisome proliferator-activated receptor beta), although it is commonly referred to and sold as a SARM (selective androgen receptor modulator). The best scientific way to categorize this drug is as a PPAR receptor agonist. It is considered an incredible endurance and fat loss drug and has been used as a doping agent by athletes for the past decade.

Development

cardarine use in olympicIt was developed originally in the early 90’s by pharma companies GlaxoSmithKline and Ligand to prevent tumors of the colon and breasts. Additional studies in the 2000’s found that PPAR agonists could slow obesity and diabetes, and during the 2008 Olympics Cardarine was heavily doped by athletes to boost endurance. It has since been added to the banned list by WADA 1)2017 LIST OF PROHIBITED SUBSTANCES AND METHODS https://www.wada-ama.org/en/prohibited-list and athletes are routinely tested for it.

Science of how it works

Cardarine being a PPAR agonist 2)PPAR agonists: multimodal drugs for the treatment of type-2 diabetes: https://www.ncbi.nlm.nih.gov/pubmed/18054742 binds to the PPAR receptor. When this happens there is an alteration of the gene activity which controls energy disbursement. This is why people say that Cardarine is exercise in a bottle, that is essentially what happens when you take the drug, without you having to actually exercise. The beauty part of it is that when you do actually exercise while using it, it will increase the benefits exponentially, and you will be actually able to push harder for longer.

Other things it does

GW-501516 also has a beneficial effect on the heart. It will decrease LDL (bad cholesterol), increase HDL (good cholesterol) and help prevent diabetes.

We all want to lose body fat, and cardarine does this by changing the way our body metabolizes nutrients. It will promote glucose uptake and drastically reduce the possibility of fat storage.

Scenarios of use and How to stack

 buy N2slinOverweight individual:

Someone who is too fat can use cardarine safely to help lose fat and boost their poor endurance conditioning. They should consider using Cardarine before exercise, with a fat blocker supplement like N2slin before meals.

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buy n2guardSteroid user:

Someone using anabolic steroids will appreciate Cardarine’s ability to burn fat WITHOUT burning muscle. This is different than other drugs like T3 or clenbuterol.

It also will help increase endurance, which harsh steroids like tren destroy. Side effects will be lowered, especially when used with N2guard support supplement.

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buy gw-501516 cardarineEndurance athletes:

Cardarine works almost immediately to improve endurance, it is literally exercise in a bottle. Take it 1-2 hours before your cardio or intense weight training and it will help you push harder. Top tier endurance athletes like to stack Cardarine with AICAR or EPO. Although in recent years the high side effect EPO has fallen out of favor, thanks to the rise in Cardarine.

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buy hcgenerateAverage joe:

The average joe gym rat who just wants a boost, wants to lose some fat, and wants to look better can use GW-501516 along with a test booster like hcgenerate to accomplish their goals.

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PCT:

Cardarine is perfectly safe to use in PCT or bridge. Remember it is nonhormonal so it has no effects on the HPTA.

Crossfit:

Cardarine is considered the #1 compound used in CrossFit because of its endurance and fat loss benefits. If you talk to anyone in a CrossFit gym they will mention this drug for this reason.

Side effects

Studies have shown no side effects, but like all drugs you should always cycle off after 8-12 weeks to give the body a break.

It is important to make sure you are using legitimate Cardarine.
Women are also safe to use Cardarine, as it is nonhormonal and will not cause any virilization 3)Virilization is the biological development of sex differences, for more information, please visit https://en.wikipedia.org/wiki/Virilization.

half life and detection times

Cardarine has a 24-hour half-life, the bad news is the detectable time is somewhere between 2-4 weeks. So if you are a tested athlete you need to avoid using it at least 1 month before your testing.

Which of the below is NOT TRUE based on recent Cardarine studies?

Dosage

Cardarine should be used between 10mg to 20mg per day, with 20mg per day being the sweet spot. I personally like to dose it all 1-2 hours before my exercise to get peak levels, but it can be taken as a split dose during the day.

Where to find

Cardarine does not cause side effects. If you do get sides on it then you are using fake cardarine, which is likely laced with pro hormone. It is only available in pill form on the black market, so if you find the product being sold as a pill over the counter, it is not real. Legally it can be acquired via research chemical in liquid form. Sarms1 brand is the top brand in the industry and the only one I would trust.

References   [ + ]

1. 2017 LIST OF PROHIBITED SUBSTANCES AND METHODS https://www.wada-ama.org/en/prohibited-list
2. PPAR agonists: multimodal drugs for the treatment of type-2 diabetes: https://www.ncbi.nlm.nih.gov/pubmed/18054742
3. Virilization is the biological development of sex differences, for more information, please visit https://en.wikipedia.org/wiki/Virilization

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