Testolone (RAD140)

Intro

Testolone, also known as RAD140, is a very potent nonsteroidal selective androgen receptor modulator (SARM).  It is currently in preclinical trials under development by Radius Health to treat muscle wasting and breast cancer.   It is very new to the fitness community, and has started to be used as a performance enhancing compound, with early reviews being very promising.

Testosterone vs. Testolone

Testolone purpose is to act as hormone replacement therapy, to replace testosterone, without the negative side effects.   It has a 90 to 0 anabolic to androgenic ratio.  This means it will not cause androgenic side effects like aggression, acne, enlarged prostate, and heart strain.   It also is nonestrogenic as well, so there will be no water retention, a risk of gyno, or bloat issues.   Testosterone meanwhile aromatizes heavily into estrogen and has a 100 androgenic rating.

There is no really good way of getting testosterone replacement therapy without injecting.  Andriol is oral based testosterone, but it has a very poor bioavailability so do not expect to get much out of it since the liver will destroy it.   Topical testosterone creams can cause rashes and have to be put on properly without contacting others while it is drying.

Testolone does not require injections or a cream application, so this is a potential major breakthrough in the medical community and fitness world.

How it works

Testolone has only been in development since 2010, so it is very new.  It works by selectively targeting androgen receptors in the body, causing an anabolic environment without side effects.  It accomplishes this by avoiding activating receptors in other parts of the body.  It just specifically activates the muscle and bone tissues.  This makes it an excellent choice for HRT (hormone replacement therapy) since it will provide an anabolic environment and prevent catabolism.  Studies have been done which show an increase in lean mass and a drop in fat tissue, typical of anabolic use.

Testolone (RAD140) Study

Primate body weight from day −21, through 28 days dosing and 21 days postdosing with RAD140 (0.01, 0.1, and 1 mg/kg, po).25 Three monkeys were included for each treatment group. The change in baseline subtracted body weight from day −1 to day 29 was statistically significant for the 0.1 mg/kg (p < 0.01) and 1.0 mg/kg (p < 0.05) groups only. The change in body weight at day 29 between the 0.1 mg/kg group and the 0.01 mg/kg group was statistically significant (p < 0.05) but not for 1.0 mg/kg and the 0.01 mg/kg group (p < 0.1).

Scenarios of use and How to stack

Testolone works great when used solo, however, stacking can enhance the benefits of this potent SARM.

One of the best ways to stack it is in a SARMs stack alongside GW and either LGD4033, S4, or Ostarine.  This type of stack will result in very low side effects while helping the athlete achieve goals of lean musle mass, strength gains, and body fat loss.   This stack is effective for gym rats or Crossfit athletes.

Another way to use it would be as part of a steroid cycle.  Many steroid junkies will insist on having a ‘test base‘ in their cycle.  So they can replace their usual dose of testosterone with Testolone and allow whatever steroid they are stacking with it to do its job without worrying about additional side effects or water retention.

Endurance athletes who want a boost in anabolic activity without dealing with negative side effects of water retention and even muscle pumps can utilize Testolone.  I recommend stacking with SR9009 or Cardarine for a potent endurance stack.  This is great for bicyclists, swimmers, or runners.

Finally, some users will simply use it to cruise with between steroid cycles rather than using testosterone.  The advantage would be less strain on the body and it would cut down on injections.

Side effects

As mentioned Testolone is nonandrogenic and nonestrogenic.  It also will not cause DHT (dihydrotestosterone) side effects like loss of hair and enlarged prostate.   The one side effect though has to do with it being such a powerful SARM and that is that it is suppressive.  It is not nearly as suppressive as anabolic steroids of course, but it is more suppressive than other SARMs in its class.  So a full PCT needs to be used after cycle, I recommend the perfect PCT 1)The perfect Post Cycle Therapy is a revolutionary PCT protocol invented by .

half life and detection times

The half-life is almost 24 hours, so once a day dosage is sufficient.   Detection times are far shorter than testosterone, giving another advantage.   Based on my best guess detection time will be only 2 weeks.

buy testolone (rad140 for sale)Dosage and how to take

Testolone can be run at 10mg per day for males, and 5mg a day for females.   In research chemical form you simply squirt into the back of the mouth, swallow, and then chase with juice.

Buy RAD140

Where to buy RAD140

Testolone is available in forms of pills or liquid.  However, fake RAD140 are surging the market, you should always buy it from a reliable source.  Sarms1 brand has been shown to be 99.9% pure so I recommend using them.

 

References   [ + ]

1. The perfect Post Cycle Therapy is a revolutionary PCT protocol invented by
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